Is Phentermine Effective for Weight Loss?

Phentermine Weight Loss Results – How much weight can you lose on phentermine?

Eating a perfectly balanced diet with regular exercise does have a positive impact on weight loss, however, some drugs speed up this process and can be used as an adjunct therapy.

Phentermine is a world-class appetite suppressing drug which is approved by the FDA around the world. [1]

The purpose of Phentermine is to induce a short-term weight loss in individuals who are at cardiovascular and blood sugar related risks.

The power of phentermine against weight gain is definite but it’s not without the risk of side effects.

Whether Phentermine is a good option for weight loss or not will be mentioned in this article.

What is Phentermine?

Phentermine is a generic formula used as a weight loss medication, available by many brand names such as Adipex, Lomaira, Elvenir, etc.

phentermine weight loss

In 1959, Phentermine was approved by FDA for short term use which should be exceeded to 12-16 weeks.

Later on in the 1990s, Phentermine was given in combination with other weight loss medication to treat higher BMI in patients with cardiovascular disease. [2]

You may have also heard one of the famous brand names of Phentermine (Qsymia) which is sold in many regions of the US and UK.

According to the laws of FDA, Phentermine is under the class of controlled substance which have similarities to amphetamine.

It can only be found with a prescription that shows the pharmacist that your doctor prescribed you to control the higher BMI that is greater than 30.

BMI higher than 27 mentions the risk of high cholesterol levels, high blood pressure, or type 2 diabetes in the majority of individuals.

How does Phentermine work?

The exact mechanism of Phentermine is available here.

Phentermine belongs to the class of drugs called “Anorectics” which are common in their appetite-suppressing effects.

Taking Phentermine has an impact on appetite and thus minimizing the caloric intake. The continuous use of Phentermine induces a remarkable weight loss by enabling the stimulation of Dopamine and Serotonin hormones.

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The level of these 2 hormones defines the well-being of a person and is used as a mood elevator which in case of less caloric intake is quite beneficial.

Phentermine also stimulates the secretion of chemical messengers or neurotransmitters such as norepinephrine.

The feeling of hunger usually gets suppressed when these hormones and neurotransmitters are present in your blood.

Some people build a tolerance with phentermine’s appetite suppressing effect within a few weeks. At this stage, the drug should not be increased in dose or discontinued.

Is Phentermine a Good Option for Weight Loss?

Like many drugs, Phentermine also exhibits a series of side effects which makes it less attractive for long-term use. [3]

Doctors around the world are following the FDA guide about the Phentermine dosage and how long you should prescribe it to your patients.

Phentermine works by suppressing appetite that is mostly linked to the stimulation of the nervous system.

The drug doesn’t work if regular exercise and strict diet plans aren’t involved. It’s not for those men and women who are seeking a short cut to losing weight, only a few pounds in weeks.

The reason why Phentermine is listed as a Schedule IV drug is that it is abused around the world. Building tolerance plus addiction is one of Phentermine’s negative outcomes.

Precautions Before Taking Phentermine

Phentermine should not be given to the patients who are allergic to its chemical structure.

Phentermine User Reviews for Weight Loss

Individuals with the following medical conditions are not allowed to use Phentermine.

  • Over-active thyroid stimulation disorder
  • Glaucoma
  • Coronary Heart Disease, Arrhythmia, Congestive Heart Failure
  • High Blood Pressure
  • Aggression in Mood
  • History of Drug abuse
  • Use of Other Diet Pills
Phentermine Drug Interactions

Never take Phentermine if you have been using a Monoamine oxidase inhibitor (MAO) or used in the past 14 days.

A serious drug interaction could take place, MAO inhibitors like linezolid, rasagiline, phenelzine, selegiline are one of those.

Before pregnancy, losing weight could be dangerous to the unborn baby.

Pregnant women should not be using phentermine during the course which doctors also advice not to take.

How Should You Take Phentermine?

Phentermine dosage is recommended by the doctors and is different from some individuals. Therefore, follow all the specific directions labeled in the leaflet of the medical guide in the box.

You can occasionally change the dosage.

Taking phentermine is easy as it is taken normally before breakfast, some people take it 2 hours after breakfast. Following the doctor’s advice in this regard is necessary. [4]

Overdosing on Phentermine can be very dangerous, exceeding the prescribed phentermine dosage could invite serious and life-threatening side effects.

Phentermine should only be taken for short term use; the effects of appetite suppression disappears after a few weeks. The drug can be addictive which is why one shouldn’t cross the normal dose.

Normally, phentermine users lose about 4 pounds within 4 weeks, if that’s not the case call your doctor at once to know if the medication is working or not.

Keep the phentermine away from moisture and heat and place the bottle in room temperature tightly closed.

Phentermine Dose

Adults with severe obesity and extra pounds on are prescribed to 8 mg of phentermine dose taken 3 times daily from the oral route.

This can be taken 30 minutes before or after meals.

Phentermine general dose 15-37.5 mg is taken once daily before breakfast.

Phentermine Weight Loss Results

Using Phentermine for short-term treatment for weight loss with the addition of weight loss exercise, caloric restriction, and behavioral modification could result in weight loss.

How quickly does Phentermine work?

The dosing of phentermine is observed to manage the exogenous obesity in patients with Body Mass Index around 30 kg/m2 or greater.

These are the patients who were at a higher risk of diabetes, hyperlipidemia, and hypertension.

Phentermine Side Effects You Should Know About

The use of Phentermine is for short-term only, the long-term use could be unsafe according to many studies. [5]

When using phentermine for a long-term, topiramate is combined alongside, both drugs are given in small doses to avoid the side effects.

Serious side effects by Phentermine are rare when you combine it with Topiramate.

Phentermine use has the following side effects which are:

  • Dizziness
  • Dry Mouth
  • Palpitation
  • Flushing
  • Sleep Disturbances
  • Muscle Fatigue
  • Constipation

How to Lose Weight Without Phentermine?

While phentermine is effective for weight loss and only aids it for a short time. Some healthy lifestyle changes could develop positive effects on the body and maintain weight loss.

This leads us to the fact that at some point the phentermine use should be discontinued.

If you haven’t made any proper changes in your lifestyle, stopping phentermine use could bring back the old fashioned unhealthy dietary intake.

Some lifestyle changes are mandatory which includes:

  • Restrictive Caloric Diet

Efficient against weight gain, eating 300-500 calories per day with Phentermine is important in which dietitians can help you design to achieve your goals.

  • Arrange Nutrient-Rich Foods

Start taking some nutrient-dense foods like fruits and vegetables, these are known for having low in calories and high in nutrients like vitamins, minerals, and fibers.

  • Physical Activity

Without a minimum of 150 minutes of moderate aerobic exercise or jog, it is impossible to lose weight even if you are using a weight loss aid.

  • Behavioral Changes

This includes controlling the insatiable cravings and self-monitoring the food intake or yours. Also, mark the physical activity chart to fulfill the lack of physical workout.

These lifestyle changes seem difficult at first but once you manage to make them, it will be invested in a good time and energy used to promote and maintain weight loss.


Phentermine is an FDA approved, Class IV schedule substance developed 70 years ago. The short-term use of Phentermine is approved for people only who are on the verge of systemic diseases.

The combination of Phentermine and Topiramate is safer for weight loss which doesn’t build tolerance like it does with phentermine alone.

You must also mind the side effects of Phentermine which are fatigue, constipation, dizziness, dry mouth, etc.

One more use of Phentermine is against Bulimia Nervosa which in combination with Topiramate is much beneficial.

Like many weight-loss drugs, Phentermine alone cannot work if you involve some lifestyle changes.

These changes could halt the lipid build-up in your blood vessels and work out with peripheral fats too which improves your look.

Natural phentermine versions in 2020 are many which also stimulates the production of dopamine but they also seem to work by progressing the normal metabolic activities there are to escalate fat loss.